Poster présenté par Dr. Juan Iovanna (Inserm U1068, Marseille, France) au copngrès annuel AACR (USA, Washington, 1-6 April 2017)

Intervention & poster IMODI au congrès annuel de l’AACR (USA, Washington, 1-6 Avril 2017)
05/04/2017
Olivier DUCHAMP, coordinateur IMODI, co-auteur du livre: Patient Derived Tumor Xenograft Models
12/05/2017

Poster présenté par Dr. Juan Iovanna (Inserm U1068, Marseille, France) au copngrès annuel AACR (USA, Washington, 1-6 April 2017)

AACR 2017 - Poster presentation - Abstract # 3846 by Dr. Juan Iovanna (Inserm U1068, Marseille, France)

AACR 2017 - Poster presentation - Abstract # 3846 by Dr. Juan Iovanna (Inserm U1068, Marseille, France)

IMODI initiative : a novel holistic and integrative approach with patient-derived tumor models against pancreatic cancer

Introduction

The national IMODI (Innovative MODels Initiative) consortium includes 25 partners (pharma, SMEs, academic research labs and clinical centers) with the aim of developing more predictive tools to improve the selection of new effective treatments to combat 9 cancer pathologies. These developments include:
  • Collection of in-vivo PDX models,
  • Collection of in-vitro derived cell lines,
  • 2D & 3D ex-vivo assays,
  • In-vivo humanized models (immune system, liver and tumour stroma),
  • Characterization of tumour histology, gene mutations, gene expression, pharmacological responses and gut microbiota,
  • Biobanks of tumours, blood, serum and stools
  • Central database,
  • Datamining,
Results on pancreatic adenocarcinoma model developments, characterization and data analysis are presented as an example of the IMODI holistic and integrative approach.
 
 
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